Liposomal Delivery

If you're interested in redeeming the most out of the amazing benefits of mushrooms, you're in the right place. Mushrooms have been used for thousands of years for their numerous health benefits, but modern research has allowed us to go a step further. 

There are already a number of different types of mushroom extracts available in the market:

1. Mushroom Powders
2. Mushroom Teas
3. Dual Extracts

The table below provides a comparison of these different types of mushroom extracts, focusing on their absorption rates and preservation.

As you can see, liposomal delivery-based extracts outshine the other forms of mushroom extracts in terms of absorption and preservation. This is because Liposomal is more than an 'extraction method' Liposomal Delivery is used for the intention of increasing how we can use the compounds found in mushrooms that have already been effectively extracted. 

The Importance of Bioavailability

When it comes to supplementing with mushrooms, one of the most crucial factors to consider is bioavailability. Bioavailability refers to the amount of a substance that is absorbed by your body and able to produce an effect. The higher the bioavailability, the more efficiently your body can use the supplement (Poulsen et al., 2014)[1].

Standard digestion can harm compounds found in mushrooms before they reach the small intestines, where they can be absorbed. This is where liposomal delivery-based extracts come into play.

Liposomal Delivery: What Is It and How Does It Work?

Liposomal delivery is a revolutionary method that utilizes liposomes to enhance the absorption and bioavailability of the active compounds found in mushrooms. Liposomes are tiny, spherical-shaped vesicles made up of phospholipids, which are the same materials that make up cell membranes (Bozzuto & Molinari, 2015)[2]. They act as carriers that encapsulate and protect the active compounds from degradation during digestion, allowing them to reach the small intestines intact.

The use of ultrasound technology in the liposomal encapsulation process further improves the stability and effectiveness of the liposomes. Ultrasound waves generate microscopic bubbles that collapse on the liposomes' surface, which creates tiny openings in the phospholipid bilayers. These openings allow the active compounds to be loaded more efficiently into the liposomes, resulting in a more stable and effective delivery system (Gulsun et al., 2019)[3].

The Benefits of Liposomal Delivery-Based Extracts

1. Enhanced Bioavailability: As mentioned earlier, liposomal delivery significantly improves the absorption rate of the active compounds found in mushrooms. This means that your body can utilize more of the beneficial compounds, maximizing the potential health benefits (Akbarzadeh et al., 2013)[4].

2. Improved Stability: Liposomes protect the active compounds from degradation during digestion, ensuring that they reach the small intestines intact. This results in a more stable and effective supplement compared to other forms of mushroom extracts (Bozzuto & Molinari, 2015)[2].

3. Targeted Delivery: The phospholipids in liposomes have an affinity for cell membranes, which allows them to deliver the active compounds directly to the target cells. This targeted delivery method can enhance the effectiveness of the mushroom compounds and reduce potential side effects (Sercombe et al., 2015)[5].

4. Improved Preservation: Liposomal delivery-based extracts have excellent preservation properties, ensuring that the active compounds maintain their potency and effectiveness for a longer period of time compared to other forms of mushroom extracts.

Liposomal delivery-based extracts represent a significant advancement in the world of mushroom supplements. With their enhanced bioavailability, improved stability, targeted delivery, and excellent preservation properties, they offer a superior option compared to traditional mushroom powders, teas, and dual extracts.

By choosing liposomal delivery-based extracts, you can ensure that you're getting the most out of your mushroom supplements, maximizing their potential health benefits. So, if you're looking to incorporate the power of mushrooms into your daily routine, liposomal delivery-based extracts are undoubtedly the way to go.

References

[1] Poulsen, M., Jensen, M. B., & Hammershøj, M. (2014). Bioavailability. In Encyclopedia of Meat Sciences (Second Edition) (pp. 179-183). Academic Press. https://doi.org/10.1016/B978-0-12-384731-7.00061-0

[2] Bozzuto, G., & Molinari, A. (2015). Liposomes as nanomedical devices. International Journal of Nanomedicine, 10, 975-999. https://doi.org/10.2147/IJN.S68861

[3] Gulsun, T., Gultekinoglu, M., Serdar Onur, A., & Bucak, S. (2019). Effects of Ultrasound on Liposomes. In Advances in Experimental Medicine and Biology (Vol. 1153, pp. 59-68). Springer. https://doi.org/10.1007/5584_2019_346

[4] Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., Hanifehpour, Y., ... & Nejati-Koshki, K. (2013). Liposome: classification, preparation, and applications. Nanoscale Research Letters, 8(1), 102. https://doi.org/10.1186/1556-276X-8-102

[5] Sercombe, L., Veerati, T., Moheimani, F., Wu, S. Y., Sood, A. K., & Hua, S. (2015). Advances and challenges of liposome assisted drug delivery. Frontiers in Pharmacology, 6, 286. https://doi.org/10.3389/fphar.2015.00286